David Vöhringer

Prof. Dr. rer. nat. David Vöhringer

W2-Professor für Infektionsabwehr und Toleranz

Department of Clinical Microbiology, Immunology and Hygiene
Infektionsbiologische Abteilung (Prof. Dr. Vöhringer)

Room: Room 0.224
Wasserturmstraße 3/5
91054 Erlangen

Research area:

The research focus of the laboratory of Prof. David Vöhringer is on the characterization of type 2 immune responses which develop upon infection with helminths (worm parasites) or during allergic inflammation. The group studies the mechanisms by which genes regulated via the interleukin (IL)-4 or IL-13 activated transcription factor STAT6 contribute to protective immunity against hookworms and to the generation of germinal centers which are required for differentiation of antigen-specific B cells and IgE-producing plasma cells. Further research activities aim at revealing the role of eosinophil, macrophage and T cell subsets during induction and resolution of inflammation in the lung and intestine. This work is complemented by investigations on the role of basophils and ILC2, two potent cytokine-producing cells of the innate immune system, for modulation of type 2 immune responses in skin and lung. The methods used include cutting-edge technologies such as single-cell RNA sequencing or multiparametric flow cytometry and immunofluorescence imaging. The research group participates in various research training groups and research units funded by the Deutsche Forschungsgemeinschaft.